basic FUNCTION
| may play an important role in the regulation of signal transduction and cellular functions |
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cytosolic adaptor protein and tyrosine kinase substrate, involved in Src- and RET/PTC-dependent signaling |
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exhibited robust translocation to the cell periphery in response to various stimuli (including epidermal growth factor, wounding and expression of constitutively active Rac) that elicit lamellipodium formation |
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Rac- and cytoskeleton-regulated and cytoskeleton-regulating adaptor protein that exhibits high affinity to lamellipodial (branched) F-actin and impacts motility and invasiveness of tumor cells |
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promotes thyroid tumor growth, and its expression in these cancer cells may affect cell proliferation and survival by controlling the expression of multiple genes, especially transcription regulators |
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could be involved in growth and survival of different cancer cells |
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adaptor protein involved in the regulation of cell proliferation, survival and migration |
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is potentially involved in the regulation of airway epithelial differentiation, especially during airway repair after injury |
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regulates cell growth, survival, and migration |
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can regulate cell growth, migration and invasion and possibly has the effect through the cAMP-SRC-phosphoinositide 3-kinase/AKT pathway |
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is required for airway epithelial repair and regeneration and interaction between AFAP1L2 and another scaffold protein, SH3PXD2A, regulates cell proliferation and survival in human bronchial epithelial cell |