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FLASH GENE
Symbol AMER3 contributors: mct - updated : 29-08-2013
HGNC name APC membrane recruitment protein 3
HGNC id 26771
Location 2q21.1      Physical location : -
Synonym name
  • putative uncharacterized protein FLJ38377
  • hypothetical protein LOC205147
  • cDNA FLJ78143
  • family with sequence similarity 123C
  • cDNA FLJ78143
  • Synonym symbol(s) FLJ38377, FAM123C
    DNA
    TYPE functioning gene
    STRUCTURE 12.63 kb     2 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    text four variants encode the same protein
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 6236 90 861 - 2010 20843316
    2 - 6172 90 861 - 2010 20843316
    - - 6169 90 861 - 2010 20843316
    2 - 6252 90 861 - 2010 20843316
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain     Mus musculus
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Nervouscentral    Mus musculus
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • conserved APC-binding (but not membrane association) motifs are preserved
  • HOMOLOGY
    Homologene
    FAMILY
  • FAM123 family
  • CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • AMER1, AMER2, AMER3 have conserved and divergent cellular roles
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS