protein
| GPE1-binding protein, GPE1-BP ( |
|
TATA-binding protein, TFIIB, the RAP30 subunit of TFIIF and the coactivator CREB-binding protein ( |
|
ZIP kinase |
|
forms a heterodimer with the bZIP domain of C/EBP beta ( |
|
transcription factor 11 (basic leucine zipper type), TCF11 ( |
|
GABAB receptor ( |
|
SKP1 interacting partner 3, SKIP3 ( |
|
Disrupted-In-Schizophrenia 1, DISC1 ( |
|
subunit 3 of RNA polymerase II, RPB3 ( |
|
Zhangfei, ZF ( |
|
p300/CBP-associated factor, PCAF ( |
|
activating transcription factor 3, ATF3 ( |
|
transcription factor of the unfolded protein response (UPR) that binds to a specific CREB/ATF site within the parkin (PARK2)promoter |
|
interaction with PTH (bone formation stimulated by PTH is in part mediated by ATF4) |
|
may be a down stream target of FGF2 signaling in osteoblasts |
|
necessary for the regulation of NUPR1 expression during leucine starvation |
|
TWIST1, TWIST2 are novel inhibitory binding partners of ATF4 |
|
is a protein interacting with EGLN2 as well as EGLN3, but not with EGLN1 |
|
functional interaction between ATF4, TXLNG, and NACA, three proteins that have been previously shown to associate using various protein-protein interaction assays |
|
FOXO1 physically interacts with and promotes the transcriptional activity of ATF4 (FOXO1 and ATF4 cooperate to increase glucose levels and decrease glucose tolerance) |
|
ATF4 activates BGLAP in osteoblasts and indian hedgehog (IHH) in chondrocytes |
|
transcriptional repressor of ATF4 during UV stress (binds to critical elements in the ATF4 promoter, resulting in its transcriptional repression) |
|
VIM, a leucine zipper-containing intermediate filament protein, suppresses ATF4-dependent osteocalcin (OCN) transcription and osteoblast differentiation |
|
FAM175B interaction with ATF4 is necessary and essential for the cytoprotective function of FAM175B following oxidative stress |
|
APLN is down-regulated by ATF4 via the pro-apoptotic MAPK14 pathway under endoplasmic reticulum (ER) stress |
|
TBL2 interacts with PKR-like ER-resident kinase (EIF2AK3), and under ER stress, it mediates protein expression of activating transcription factor 4 (ATF4) |
|
under ER stress, TBL2 participates in ATF4 translation through its association with the mRNA |
|
role of ATF4 in the SESN2 gene upregulation induced by mitochondrial dysfunction |
|
ATF4 could maintain SREBF1 protein stability by directly activating the expression of USP7 which deubiquitinates SREBF1 and increases its protein content in cell |
|
chenodeoxycholic acid (CDCA) regulation of FGF21 transcription is mediated at least partially by an EIF2A-dependent increase in ATF4 expression |
|
beneficial role of hypothalamic ATF4/ATG5 axis in the regulation of energy expenditure, obesity, and obesity-related metabolic disorders |
|
DELE1 is required for ATF4 translation downstream of EIF2A phosphorylation |
|
among UPR-related transcription factors, XBP1 upregulated ACTN2, whereas XBP1, ATF4 and ATF6 downregulated ACTN3 promoter activity |