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FLASH GENE
Symbol EIF3B contributors: - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit B
HGNC id 3280
Location 7p22.2      Physical location : 2.394.473 - 2.420.375
Synonym name
  • eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa
  • Synonym symbol(s) PRT1, EIF3-ETA, EIF3-P110, EIF3-P116, EIF3S9
    DNA
    TYPE functioning gene
    STRUCTURE 25.00 kb     19 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 3009 - 814 - ElAntak
    - - 3084 - 814 - ElAntak
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
     mouth   highly
    Respiratoryrespiratory tractlarynx  highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    a RNA recognition motif, RRM
    HOMOLOGY
    interspecies homolog to yeast S.cerevisiae Prt1
    Homologene
    FAMILY eukaryotic translation initiation factor family
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
  • promoting the association of Met-tRNA and mRNA
  • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component components of the EIF3 multiprotein complex, 600kDa
    INTERACTION
    DNA
    RNA binding to the 40S ribosome
    small molecule
    protein EIF3A
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS