Rna function
| long nuclear-retained regulatory RNA (nrRNA), having a role in Alternative splicing regulation, by modulating the levels of active serine/arginine (SR) proteins |
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expressed in numerous tissues and is highly abundant in neurons |
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may regulates synapse formation by modulating the expression of genes involved in synapse formation and/or maintenance |
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serine-rich proteins and MALAT1 facilitate the association of several of the pre-mRNA processing factors on a chromatin locus |
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SRSF1 along with MALAT1 could influence the recruitment of splicing factors to nuclear speckles |
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MALAT1 influenced the speckle association of SRSF1 in a phosphorylation-independent manner |
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role of MALAT1 in cellular transformation |
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MALAT1 directly interacted with SP1 and LTBP3 promoter to increase expression of LTBP3 gene |
Type
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