Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MAN2C1 | contributors: mct/npt - updated : 08-03-2022 |
HGNC name | mannosidase, alpha, class 2C, member 1 |
HGNC id | 6827 |
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Corresponding disease |
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Location | 15q24.2 Physical location : 75.648.134 - 75.660.941 | ||
Synonym name | |||
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Synonym symbol(s) | MANA, MAN6A8, MANA1, MGC87979, DKFZp686E23167 | ||
EC.number | 3.2.1.24 |
DNA |
TYPE | functioning gene |
STRUCTURE | 12.82 kb 26 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | ortholog to murine Man2c1 |
ortholog to rattus man2c1 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,cytosolic | |
intracellular,nucleus,nucleoplasm | |
text | type II transmembrane protein |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Other | regulation of MAN2C1 expression is essential for maintaining efficient protein N-glycosylation |
ASSOCIATED DISORDERS |
corresponding disease(s) | CDDG2 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |
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