Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | MAZ | contributors: mct - updated : 09-03-2018 |
HGNC name | MYC-associated zinc finger protein (purine-binding transcription factor) |
HGNC id | 6914 |
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Location | 16p11.2 Physical location : 29.817.854 - 29.822.502 |
Synonym name | |
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Synonym symbol(s) | PUR1, ZF87, SAF2, SAF1, Zif87, ZNF801 |
DNA |
TYPE | like-sequence |
STRUCTURE | 5.10 kb 6 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | cytosine-phosphate-guanine/HTF |
MAPPING | cloned | Y | linked | status | confirmed |
Map | pter - D16S3093 - KIF22 - MAZ - D16S409 - cen |
Authors | GeneMap 98 (NCBI) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of | housekeeping |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | PhosphoP |
HOMOLOGY |
interspecies | homolog to murine Maz (98,59 pc) |
Homologene |
FAMILY |
CATEGORY | transcription factor , tumor suppressor |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,nucleus |
basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, transcription, initiation |
nucleotide, transcription, termination | |
nucleotide, transcription, regulation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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MAZ is essential to bypass MYB promoter repression by RB1 family members and to induce MYB expression |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |