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FLASH GENE
Symbol MYL6 contributors: npt/ - updated : 10-01-2006
HGNC name myosin, light chain 6, alkali, smooth muscle and non-muscle
HGNC id 7587
Location 12q12      Physical location : 56.552.099 - 56.555.366
Synonym name
  • myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
  • myosin light chain alkali 3
  • myosin light polypeptide 6
  • Synonym symbol(s) ESMLC, LC17A, LC17B, MLC1SM, MLC3NM, MLC3SM, LC17-GI, LC17-NM
    DNA
    TYPE functioning gene
    STRUCTURE 3.27 kb     7 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 704 16.8 151 - Lenz (1989)
    lack exon 3
    6 - 713 16.8 116 - Lenz (1989)
    lack exons 3-7
    - - 674 13 116 - Lenz (1989)
    lack exons 1-3
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticthymus    
    Cardiovascularheart    
    Endocrinepancreas    
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    Muscularsmooth   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period fetal
    Text pancreas
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • EF-hand, calcium binding motif
  • mono polymer hexamer
    HOMOLOGY
    interspecies homolog to murine Myln
    Homologene
    FAMILY
    CATEGORY structural protein
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may be modulating the interaction between myosin and actin
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS