basic FUNCTION
| with Monad (WDR92), may function as a novel modulator of apoptosis pathway |
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promotes TNFA-induced apoptosis through death receptor-mediated caspase-3 activation pathway |
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modulates UV-induced DNA damage by regulating H2AX phosphorylation |
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with binding to WDR92 and PIH1D1, regulates apoptosis, indicating the possibility that the function of the R2TP/prefoldin-like complex (containing WDR92) may be related to the regulation of apoptosis in mammalian cells |
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RPAP3 and WDR92 promote apoptosis |
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may be a novel modulator of NF-kappaB pathway in apoptosis induced by anti-cancer chemotherapeutic agents |
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might be a powerful tool to enhance cytotoxicity of anti-cancer agents against breast cancer |