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FLASH GENE
Symbol SNX16 contributors: - updated : 07-06-2005
HGNC name sorting nexin 16
HGNC id 14980
Location 8q21.13      Physical location : 82.711.819 - 82.754.521
Synonym symbol(s) SNXG
DNA
TYPE functioning gene
STRUCTURE 39.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 3308 - 344 - Teasdale
- splicing 3141 - 344 - Teasdale
- splicing 3054 - 315 - Teasdale
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systembreast   
 male systemtestis   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cells
SystemCellPubmedSpeciesStageRna symbol
Respiratoryepithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one PX (phosphoinositide binding protein )
  • a potential coiled-coil domain important for homo-oligomerization and necessary for localization to the later endosomal structures
  • a C-terminal region
  • HOMOLOGY
    Homologene
    FAMILY sorting nexin family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endosome
    intracellular,cytoplasm,organelle,lysosome
    basic FUNCTION
  • involved in several stage of intracellular trafficking
  • may function in the trafficking of proteins between the early and late endosomal compartments
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS