basic FUNCTION
| phosphorylating cofilin and inducing actin cytoskeletal reorganization |
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putatively involved in signal transduction |
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playing a critical role in integrin-mediated actin cytoskeletal reorganization and cell spreading |
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playing an important role at and after the meiotic phase of spermatogenesis |
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the three-way interaction between SPRED1, TAOK1, and TESK1 represents a pathway that links regulation of both the microtubule- and F-actin cytoskeleton (Johne 2008) |
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plays important roles in promyelinating Schwann cells (SCs), potentially through subcellular localization change and participation in integrin-mediated actin reorganization |
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TESK1 regulates podocyte cytoskeletal dynamics in glomerular podocytes and may play an important role in regulating glomerular filtration barrier integrity in glomerular disease processes |