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FLASH GENE
Symbol XYLB contributors: mct - updated : 01-09-2014
HGNC name xylulokinase homolog (H. influenzae)
HGNC id 12839
Location 3p22.2      Physical location : 38.388.250 - 38.456.467
Synonym name xylulokinase (H. influenzae) homolog
Synonym symbol(s) FLJ10343, FLJ12539, FLJ22075, XK
EC.number 2.7.1.17
DNA
TYPE functioning gene
STRUCTURE 68.23 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map pter - XYLB - PLCD1 - C3orf8 - ITGA9 - TGP230L - cen
Authors Tamari (98)
regionally located located between OCTL2 and ActRIIB
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
19 - 3683 58.4 536 - 2013 23179721
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly Homo sapiens
Endocrinepancreas   moderately Homo sapiens
cells
SystemCellPubmedSpeciesStageRna symbol
Digestivehepatocyte Homo sapiens
Endocrineislet cell (alpha,beta...) Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to Drosophila CG3534
Homologene
FAMILY
  • FGGY kinase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • playing important roles in energy metabolism
  • xylulokinase activity
  • last enzyme in the glucuronate-xylulose pathway, active in the liver and kidneys
  • final enzyme in the glucuronate-xylulose pathway, producing a key regulator of lipogenesis, xylulose 5-phosphate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate , energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   deletion    
    in various carcinomas
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS