Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol YEATS2 contributors: mct/npt - updated : 14-02-2009
HGNC name YEATS domain containing 2
HGNC id 25489
Location 3q27.1      Physical location : 183.415.605 - 183.530.413
Synonym symbol(s) FLJ10201, FLJ12841, FLJ13308, KIAA1197, FLJ33401, FLJ34335
DNA
TYPE functioning gene
STRUCTURE 114.81 kb     31 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
31 - 6524 150.65 1422 - Beausoleil (2004)
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a "YEATS" (YNK7-ENL-AF9-TFIIF Small subunit) domain near its N terminus (Wang 2008)
  • C terminal histone fold domain
  • HOMOLOGY
    Homologene
    FAMILY
  • YEATS family
  • CATEGORY storage
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • scaffolding subunit of the ATAC complex (Wang 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of a GCN5/PCAF/TADA3L/YEATS2/CCDC101 Complex (ATAC) distinct from STAGA (Wang 2008)
  • both STAGA and ATAC acetylate specifically nucleosomal histone H3 (Wang 2008)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • STAGA and ATAC complexes physically couple distinct kinase signaling pathways to regulation of chromatin structure and gene-specific transcription and that ATAC complexes may control transcription both positively and negatively at the level of chromatin modification and via direct interactions with the TATA-binding protein (TBP) (Wang 2008)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS